{"id":5648,"date":"2025-06-26T15:23:12","date_gmt":"2025-06-26T06:23:12","guid":{"rendered":"https:\/\/aizoth.com\/?post_type=use_case&#038;p=5648"},"modified":"2026-04-17T13:48:10","modified_gmt":"2026-04-17T04:48:10","slug":"contents-e001","status":"publish","type":"use_case","link":"https:\/\/aizoth.com\/en\/use_case\/contents-e001\/","title":{"rendered":"Tailor-made Medical Care for Patients with Chronic Low Back Pain Using Multi-Sigma\u00ae"},"content":{"rendered":"\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-black-color has-text-color has-background has-link-color has-medium-font-size has-custom-font-size wp-element-button\" href=\"https:\/\/aizoth.com\/en\/blog\/multi-sigma_2025_03_27\/\" style=\"background-color:#ffe200\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>More Details<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\"><strong>Multi-Sigma<sup>\u00ae<\/sup> learns from data on patients with chronic low back pain to propose the most suitable treatment plan for each patient.<\/strong><\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" style=\"font-size:30px;text-decoration:underline\"><strong>1. Prediction of Treatment Outcomes Using Multi-Sigma<\/strong><sup>\u00ae<\/sup><\/h2>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">By utilizing the AI prediction functionality of Multi-Sigma<sup>\u00ae<\/sup>, it is possible to train an AI model using input and output data to capture their interrelationship. This AI model can then be used to accurately predict the degree of pain relief for new patients based on their input data.<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"376\" src=\"https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/image-42-1024x376.png\" alt=\"1. Prediction of Treatment Outcomes Using Multi-Sigma\u00ae\" class=\"wp-image-5028\" srcset=\"https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/image-42-1024x376.png 1024w, https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/image-42-300x110.png 300w, https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/image-42.png 1068w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:80px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" style=\"font-size:30px;text-decoration:underline\"><strong>2. Contribution Analysis of Pain Relief Using Multi-Sigma<\/strong><sup>\u00ae<\/sup><\/h2>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">By utilizing the contribution analysis function of Multi-Sigma<sup>\u00ae<\/sup>, it is possible to examine the factors that contribute positively or negatively to the degree of pain relief.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100px\">\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-medium-font-size wp-block-paragraph\"><strong>Positive contribution<\/strong><br>-initial pain value<br>-physical therapy<br>-exercise therapy<br>-CBT<br>-pharmacotherapy<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-medium-font-size wp-block-paragraph\"><strong>Negative contribution<\/strong><br>-duration of pain<br>-BMI<br>-age<br>-depressive symptoms<br>-sleep disorders<\/p>\n<\/div>\n<\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"585\" src=\"https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/EIGO_koushuueisei_FA-1024x585.png\" alt=\"2. Contribution Analysis of Pain Relief Using Multi-Sigma\" class=\"wp-image-5031\" srcset=\"https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/EIGO_koushuueisei_FA-1024x585.png 1024w, https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/EIGO_koushuueisei_FA-300x171.png 300w, https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/EIGO_koushuueisei_FA.png 1400w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:80px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" style=\"font-size:30px;text-decoration:underline\"><br><strong>3. Tailor-Made Treatment Proposal Using Multi-Sigma<\/strong><sup>\u00ae<\/sup><\/h2>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">By utilizing Multi-Sigma<sup>\u00ae<\/sup>&#8216;s tailor-made optimization function\u2014which optimizes the treatment based on fixed values in the patient data\u2014an optimal tailor-made treatment plan can be proposed to maximize that patient\u2019s pain relief.<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"413\" src=\"https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/image-43-1024x413.png\" alt=\"3. Tailor-Made Treatment Proposal Using Multi-Sigma\u00ae\" class=\"wp-image-5029\" srcset=\"https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/image-43-1024x413.png 1024w, https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/image-43-300x121.png 300w, https:\/\/aizoth.com\/wp-content\/uploads\/2025\/04\/image-43.png 1704w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">For example, by utilizing the AI model and fixing variables (such as age) for a specific patient, an optimal treatment plan\u2014including physical therapy, exercise therapy, pharmacotherapy, and CBT\u2014 can be proposed to maximize pain relief.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Note<\/strong>: This analysis is based on synthetic data, and in actual clinical practice, decisions must be made in accordance with the relevant guidelines.<\/p>\n\n\n\n<p class=\"has-small-font-size wp-block-paragraph\">Note 1: The duration of pain is displayed in months.&nbsp;<br>Note 2: The initial pain value represents the initial pain VAS score (5\u201310).&nbsp;<br>Note 3: Sleep disorders are indicated by the presence or absence of sleep disorders (0: none, 1: present).&nbsp;<br>Note 4: Depressive symptoms are indicated by the presence or absence of depressive symptoms (0: none, 1: present).&nbsp;<br>Note 5: Physical therapy is displayed as the frequency of sessions (sessions per week).&nbsp;<br>Note 6: Exercise therapy is displayed as the intensity of exercise therapy (0\u20132).&nbsp;<br>Note 7: Pharmacotherapy is displayed as follows: (0: none, 1: NSAIDs, 2: non-NSAID analgesics).&nbsp;<br>Note 8: Cognitive behavioral therapy is displayed as the implementation of CBT (0: none, 1: present).<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons 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